Name: Recombinant Human ULBP1 Protein
Brand: Beta LifeScience
SKU: BL-4890PS
Availability: InStock

Catalog No.: BL-4890PS

Product Overview

Tag	N/A
Host Species	Human
Synonym	UL16 Binding Protein 1, Retinoic Acid Early Transcript 1I, alcan-beta, NKG2D Ligand 1, NKG2DL1, RAET1I, N2DL-1, NKG2D ligand 1, ULBP.
Background	ULBP1 together with at least ULBP2 and ULBP3, is ligand for the NKG2D receptor. ULBPs stimulate various signaling pathways in primary NK cells, which result in cytokines and chemokines production. In CMV infected cells, ULBP1 cooperates with soluble CMV glycoprotein UL16 to inhibit the interaction with the NKG2D receptor providing a mechanism by which CMV infected cells escape the immune system. Additionally, UL16 retains ULBP1 to the ER and cis-Golgi apparatus to prevent it from reaching cell surface.
Description	ULBP1 Human Recombinant expressed in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 200a.a. (26-216) and having a molecular weight of 23.4kDa (Molecular size on SDS-PAGE will appear at approximately 20-40kDa).ULBP1 is fused to a 6a.a. IgG His-Tag at C-terminus and purified by unique purification methods.
Source	Sf9
AA Sequence	ADLGWVDTHC LCYDFIITPK SRPEPQWCEV QGLVDERPFL HYDCVNHKAK AFASLGKKVN VTKTWEEQTE TLRDVVDFLK GQLLDIQVEN LIPIEPLTLQ ARMSCEHEAH GHGRGSWQFL FNGQKFLLFD SNNRKWTALH PGAKKMTEKW EKNRDVTMFF QKISLGDCKM WLEEFLMYWE QMLDPTKPPS LAPGHHHHHH.
Purity	>90.0% as determined by analysis by SDS-PAGE.
Endotoxin	<1.0 EU per μg by the LAL method.
Formulation	ULBP1 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability	Recombinant protein is stable for 12 months at -70°C
Usage	For Research Use Only
Storage	Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.