Recombinant Human Troponin C Protein
Beta LifeScience
SKU/CAT #: BLPSN-4678
Recombinant Human Troponin C Protein
Beta LifeScience
SKU/CAT #: BLPSN-4678
Catalog No.: BLPSN-4678
Product Overview
| Tag | N/A |
| Host Species | Human |
| Accession | NP_003271.1 |
| Synonym | CMD1Z, CMH13, TN-C, TNC, TNNC |
| Background | Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. |
| Description | A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified. |
| Source | E.coli |
| Predicted N Terminal | Ser 21 |
| AA Sequence | Met1-Glu161 |
| Molecular Weight | The recombinant human TNNC1 consists of 161 a.a. and has a predicted molecular mass of 18.4 kDa. The apparent molecular mass of it is approximately 20 kDa in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
