Recombinant Human TREML1 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0050NP
Recombinant Human TREML1 Protein (Fc Tag)

Recombinant Human TREML1 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0050NP
Catalog No.: BL-0050NP

Product Overview

Tag Fc
Host Species Human
Accession Q86YW5
Synonym TREML1 Trem-Like Transcript 1 Protein; TLT-1; Triggering Receptor Expressed on Myeloid Cells-Like Protein 1; TREML1; TLT1
Background Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
Description Recombinant Human Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 is expressed by our Mammalian expression system and the target gene encoding Gln16-Pro162 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Gln16-Pro162
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human TREML1 Protein was lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human TREML1 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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