Recombinant Human TPK1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-4613
Recombinant Human TPK1 Protein (His Tag)

Recombinant Human TPK1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-4613
Catalog No.: BLPSN-4613

Product Overview

Tag His
Host Species Human
Accession P02775
Synonym HTPK1, PP20, THMD5
Background Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.
Description A DNA sequence encoding the human TPK1 (AAH68460.1) (Met1-Ser243) was expressed with a His tag at the N-terminus.
Source E.coli
Predicted N Terminal His
AA Sequence Met1-Ser243
Molecular Weight The recombinant human TPK1 consists of 261 a.a. and predicts a molecular mass of 29.5 KDa. It migrates as an approximately 27-32 KDa band in SDS-PAGE under reducing conditions.
Purity >90% as determined by SDS-PAGE
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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