Recombinant Human TBC1D22B Protein

Beta LifeScience SKU/CAT #: BL-4270PS
Recombinant Human TBC1D22B Protein

Recombinant Human TBC1D22B Protein

Beta LifeScience SKU/CAT #: BL-4270PS
Catalog No.: BL-4270PS

Product Overview

Tag N/A
Host Species Human
Synonym TBC1 Domain Family, Member 22B, C6orf197, Chromosome 6Open Reading Frame 197, TBC1 Domain Family Member22B, TBC1 domain family member 22B.
Background TBC1 domain family member 22B, also known as TBC1D22B acts as a GTPase-activating protein for Rab family protein. The Tre-2/Bub2/Cdc16 (TBC) domainis a conserved protein motif which consists of roughly 200aa andfunctions as a specific Rab-GAP domain. The TBC domain has more than 40 distinctTBC domain-containing proteins which have been identified in humans.
Description TBC1D22B Human Recombinant expressed in E.Coli is asingle, non-glycosylated polypeptide chain containing 528a.a. (1-505 a.a)and having a molecular weight of 61.5kDa.TBC1D22B is fused to a 23a.a. His-tag atN-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMAAENSK QFWKRSAKLP GSIQPVYGAQ HPPLDPRLTK NFIKERSKVNTVPLKNKKAS SFHEFARNTS DAWDIGDDEE EDFSSPSFQT LNSKVALATA AQVLENHSKL RVKPERSQSTTSDVPANYKV IKSSSDAQLS RNSSDTCLRN PLHKQQSLPL RPIIPLVARI SDQNASGAPP MTVREKTRLEKFRQLLSSQN TDLDELRKCS WPGVPREVRP ITWRLLSGYL PANTERRKLT LQRKREEYFG FIEQYYDSRNEEHHQDTYRQ IHIDIPRTNP LIPLFQQPLV QEIFERILFI WAIRHPASGY VQGINDLVTP FFVVFLSEYVEEDVENFDVT NLSQDMLRSI EADSFWCMSK LLDGIQDNYT FAQPGIQKKV KALEELVSRI DEQVHNHFRRYEVEYLQFAF RWMNNLLMRE LPLRCTIRLW DTYQSEPEGF SHFHLYVCAA FLIKWRKEIL DEEDFQGLLMLLQNLPTIHW GNEEIGLLLA EAYRLKYMFA DAPNHYRR.
Purity >80% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation TBC1D22B protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4) 30% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
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