Recombinant Human SYCE3 Protein

Beta LifeScience SKU/CAT #: BL-4259PS
Recombinant Human SYCE3 Protein

Recombinant Human SYCE3 Protein

Beta LifeScience SKU/CAT #: BL-4259PS
Catalog No.: BL-4259PS

Product Overview

Tag N/A
Host Species Human
Synonym Synaptonemal complex central element protein 3, chromosome 22 open reading frame 41, Testis highly expressed gene 2 protein, testis highly expressed protein 2, THEG2, C22orf41.
Background Synaptonemal complex central element protein 3 (SYCE3) is key component of the transverse central element of synaptonemal complexes (SCS). The synaptonemal complex is a protein structure which forms between homologous chromosomes (2 pairs of sister chromatids) during meiosis and is assumed to mediate chromosome pairing, synapsis, and recombination (crossing-over). The SYCE3 protein is essential for chromosome loading of the central element-specific SCS proteins, as well as for initiating synapsis between homologous chromosomes. SYCE3 is also vital for fertility.
Description SYCE3 Human Recombinant expressed in E. coli is a single polypeptide chain containing 108a.a. (1-88) and having a molecular weight of 12.8 kDa.SYCE3 is fused to a 20a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MDDADPEERN YDNMLKMLSD LNKDLEKLLE EMEKISVQAT WMAYDMVVMR TNPTLAESMR RLEDAFVNCK EEMEKNWQEL LHETKQRL
Purity >90% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The SYCE3 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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