Recombinant Human STK38L/Ndr2 Protein
Beta LifeScience
SKU/CAT #: BLA-8568P
Recombinant Human STK38L/Ndr2 Protein
Beta LifeScience
SKU/CAT #: BLA-8568P
Collections: Other recombinant proteins, Recombinant proteins
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Product Overview
Host Species | Human |
Accession | Q9Y2H1 |
Synonym | KIAA0965 NDR2 NDR2 protein kinase nuclear Dbf2 related 2 Nuclear Dbf2 related kinase 2 Nuclear Dbf2-related kinase 2 Serine/threonine protein kinase 38 like Serine/threonine-protein kinase 38-like ST38L_HUMAN Stk38l |
Description | Recombinant Human STK38L/Ndr2 Protein was expressed in Baculovirus infected Sf9 cells. It is a Full length protein |
Source | Baculovirus infected Sf9 cells |
Molecular Weight | 82 kDa including tags |
Purity | >90% Densitometry.Purity determined to be >90% by densitometry. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | The specific activity of this recombinant protein was determined to be 2 nmol/min/mg. |
Formulation | Liquid Solution |
Stability | The recombinant protein samples are stable for up to 12 months at -80°C |
Reconstitution | See related COA |
Unit Definition | For Research Use Only |
Storage Buffer | Shipped on dry ice. Upon delivery aliquot and store at -80°C. Avoid freeze / thaw cycle. |
Target Details
Target Function | Involved in the regulation of structural processes in differentiating and mature neuronal cells. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Membrane. Note=Associated with the actin cytoskeleton. Co-localizes with STK24/MST3 in the membrane. |
Protein Families | Protein kinase superfamily, AGC Ser/Thr protein kinase family |
Database References | |
Tissue Specificity | Ubiquitously expressed with highest levels observed in the thymus. |
Gene Functions References
- It was found that STK38L*I/D genotype had positive association with longevity in the ethnically homogeneous group of Tatars from the Republic of Bashkortostan, Russia. PMID: 28556638
- NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by triggering the switch in binding specificity of Rabin8 from PS to Sec15. PMID: 23435566
- Activation of NDR2 is a multistep process involving phosphorylation of the hydrophobic motif site Thr444/2 by MST3, autophosphorylation of Ser281/2, and binding of MOB1A. PMID: 16314523
- NDR2 is an upstream kinase of ARK5 that plays an essential role in tumor progression through ARK5 PMID: 16488889