Recombinant Human SRP14 Protein

Beta LifeScience SKU/CAT #: BL-4637PS
Recombinant Human SRP14 Protein

Recombinant Human SRP14 Protein

Beta LifeScience SKU/CAT #: BL-4637PS
Catalog No.: BL-4637PS

Product Overview

Tag His
Host Species Human
Synonym Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein, ALURBP, MGC14326.
Background SRP14 is a ribonucleoprotein complex which mediates the directing of proteins to the endoplasmic reticulum. The -€œAlu domain-€ of SRP is comprised of the heterodimer of the SRP9 and SRP14 proteins that are bound to the 5' and 3' terminal sequences of SRP RNA. SRP9/14 binding may be critical to the transcription, maturation, nucleolus localization and transport of SRP RNA.
Description SRP14 Human Recombinant fused with a 24a.a. His tag at N-terminus expressed in E.Coli is a single, non-glycosylated, polypeptide chain containing 160a.a. (1-136 a.a.) and having a molecular weight of 17.1kDa. The SRP14 is purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSHMVLLES EQFLTELTRL FQKCRTSGSV YITLKKYDGR TKPIPKKGTV EGFEPADNKC LLRATDGKKK ISTVVSSKEV NKFQMAYSNL LRANMDGLKK RDKKNKTKKT KAAAAAAAAA PAAAATAATT AATTAATAAQ.
Purity >85.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The SRP14 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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