Recombinant Human SRP14 Protein
Beta LifeScience
SKU/CAT #: BL-4637PS
Recombinant Human SRP14 Protein
Beta LifeScience
SKU/CAT #: BL-4637PS
Catalog No.: BL-4637PS
Product Overview
| Tag | His |
| Host Species | Human |
| Synonym | Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein, ALURBP, MGC14326. |
| Background | SRP14 is a ribonucleoprotein complex which mediates the directing of proteins to the endoplasmic reticulum. The -€œAlu domain-€ of SRP is comprised of the heterodimer of the SRP9 and SRP14 proteins that are bound to the 5' and 3' terminal sequences of SRP RNA. SRP9/14 binding may be critical to the transcription, maturation, nucleolus localization and transport of SRP RNA. |
| Description | SRP14 Human Recombinant fused with a 24a.a. His tag at N-terminus expressed in E.Coli is a single, non-glycosylated, polypeptide chain containing 160a.a. (1-136 a.a.) and having a molecular weight of 17.1kDa. The SRP14 is purified by unique purification methods. |
| Source | E.coli |
| AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMVLLES EQFLTELTRL FQKCRTSGSV YITLKKYDGR TKPIPKKGTV EGFEPADNKC LLRATDGKKK ISTVVSSKEV NKFQMAYSNL LRANMDGLKK RDKKNKTKKT KAAAAAAAAA PAAAATAATT AATTAATAAQ. |
| Purity | >85.0% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | The SRP14 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
