Recombinant Human SRA1 Protein

Beta LifeScience SKU/CAT #: BL-4238PS
Recombinant Human SRA1 Protein

Recombinant Human SRA1 Protein

Beta LifeScience SKU/CAT #: BL-4238PS
Catalog No.: BL-4238PS

Product Overview

Tag N/A
Host Species Human
Synonym pp7684, SRA, SRAP, STRAA1, Steroid receptor RNA activator 1,Steroid receptor RNA activator protein.
Background Steroid receptor RNA activator 1 (SRA1) occurs as both an RNA transcript and as constantly expressed proteins. In addition, SRA1 mediates transcriptional coactivation of steroid receptors ligand-dependently via the steroid-binding domain (AF-2). SRA1 augments cellular proliferation and differentiation and stimulates apoptosis in vivo. SRA1 has a role in tumorigenesis. SRA1 participates in some activities such as: metabolism, adipogenesis and chromatin organization.
Description SRA1 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 170a.a. (90-236 a.a.) and having a molecular weight of 18.7kDa.SRA1 is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSVGSGPAS GVEPTSFPVE SEAVMEDVLR PLEQALEDCR GHTRKQVCDD ISRRLALLQE QWAGGKLSIP VKKRMALLVQ ELSSHRWDAA DDIHRSLMVD HVTEVSQWMV GVKRLIAEKR SLFSEEAANE EKSAATAEKN HTIPGFQQAS
Purity >85.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation SRA1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0) , 0.1MNaCl ,10% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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