Recombinant Human SOX2 Protein, TAT
Beta LifeScience
SKU/CAT #: BL-4693PS
Recombinant Human SOX2 Protein, TAT
Beta LifeScience
SKU/CAT #: BL-4693PS
Catalog No.: BL-4693PS
Product Overview
| Tag | N/A |
| Host Species | Human |
| Synonym | MCOPS3, ANOP3, MGC2413, SOX2, SRY (sex determining region Y)-box 2. |
| Background | SOX2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX4 is important for early embryogenesis and for embryonic stem cell pluripotency. |
| Description | Sox2 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 330a.a. (317 a.a. residues of the full length Sox2) and having a molecular weight of 36kDa.Sox2 is fused to a 13a.a. TAT peptide at C-terminus (GGYGRKKRRQRRR) and purified by unique purification methods. |
| Source | E.coli |
| AA Sequence | MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHMGGY GRKKRRQRRR. |
| Purity | >95.0% as determined by RP-HPLC and SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | Lyophilized from a 0.2µm filtered concentrated solution in 2xPBS, pH 7.4 and 5% trehalose. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Lyophilized Sox2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Sox2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
