Recombinant Human SOX2 Protein, TAT

Beta LifeScience SKU/CAT #: BL-4693PS
Recombinant Human SOX2 Protein, TAT

Recombinant Human SOX2 Protein, TAT

Beta LifeScience SKU/CAT #: BL-4693PS
Catalog No.: BL-4693PS

Product Overview

Tag N/A
Host Species Human
Synonym MCOPS3, ANOP3, MGC2413, SOX2, SRY (sex determining region Y)-box 2.
Background SOX2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX4 is important for early embryogenesis and for embryonic stem cell pluripotency.
Description Sox2 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 330a.a. (317 a.a. residues of the full length Sox2) and having a molecular weight of 36kDa.Sox2 is fused to a 13a.a. TAT peptide at C-terminus (GGYGRKKRRQRRR) and purified by unique purification methods.
Source E.coli
AA Sequence MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHMGGY GRKKRRQRRR.
Purity >95.0% as determined by RP-HPLC and SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 2xPBS, pH 7.4 and 5% trehalose.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Lyophilized Sox2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Sox2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
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