Recombinant Human SNAPC1 Protein

Beta LifeScience SKU/CAT #: BL-4213PS
Recombinant Human SNAPC1 Protein

Recombinant Human SNAPC1 Protein

Beta LifeScience SKU/CAT #: BL-4213PS
Catalog No.: BL-4213PS

Product Overview

Tag N/A
Host Species Human
Synonym PTFgamma, SNAP43, snRNA-activating protein complexsubunit 1, SNAPc subunit 1, Proximal sequence element-binding transcriptionfactor subunit gamma, PSE-binding factor subunit gamma, PTF subunit gamma, Smallnuclear RNA-activating complex polypeptide 1, SNAPc 43 kDa subunit, SNAPC1.
Background Small Nuclear RNA Activating Complex, Polypeptide 1 (SNAPC1) is a part of the SNAPc complex necessary for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC1 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Moreover, SNAPC1 recruits TBP and BRF2 to the U6 snRNA TATA box.
Description SNAPC1 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 391a.a. (1-368 a.a) and having a molecular weight of 45.4kDa.SNAPC1 is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMGTPPGL QTDCEALLSR FQETDSVRFE DFTELWRNMK FGTIFCGRMRNLEKNMFTKE ALALAWRYFL PPYTFQIRVG ALYLLYGLYN TQLCQPKQKI RVALKDWDEV LKFQQDLVNAQHFDAAYIFR KLRLDRAFHF TAMPKLLSYR MKKKIHRAEV TEEFKDPSDR VMKLITSDVL EEMLNVHDHYQNMKHVISVD KSKPDKALSL IKDDFFDNIK NIVLEHQQWH KDRKNPSLKS KTNDGEEKME GNSQETERCERAESLAKIKS KAFSVVIQAS KSRRHRQVKL DSSDSDSASG QGQVKATRKK EKKERLKPAG RKMSLRNKGNVQNIHKEDKP LSLSMPVITE EEENESLSGT EFTASKKRRK H.
Purity >80.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation SNAPC1 protein solution (1mg/ml) contains 20mM Tris-HCl (pH 8.0) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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