Recombinant Human SERPINB3 Protein

Beta LifeScience SKU/CAT #: BL-4609PS
Recombinant Human SERPINB3 Protein

Recombinant Human SERPINB3 Protein

Beta LifeScience SKU/CAT #: BL-4609PS
Catalog No.: BL-4609PS

Product Overview

Tag N/A
Host Species Human
Synonym Serpin B3, Squamous cell carcinoma antigen 1, ProteinT4-A, SCCA-1, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, SCCA1, Serine (Or Cysteine) Proteinase Inhibitor, Clade B(Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, Protein T4-A, SCCA-1,Serpin B3, HsT1196, SCCA-PD, T4-A , SCCA, SCC.
Background SerpinPeptidase Inhibitor, Clade B Member 3, also known as SERPINB3 is a papain-likecysteine protease inhibitor which modulates the host immune response versus tumorcells. SERPINB3 is a protein coding gene which acts as an inhibitor of UV-inducedapoptosis by suppressing the activity of c-Jun NH(2)-terminal kinase (JNK1).
Description SERPINB3 Human Recombinant expressed in E.Coli is asingle, non-glycosylated polypeptide chain containing 413a.a. (1-390 a.a)and having a molecular weight of 47kDa.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMNSLSEA NTKFMFDLFQ QFRKSKENNI FYSPISITSA LGMVLLGAKDNTAQQIKKVL HFDQVTENTT GKAATYHVDR SGNVHHQFQK LLTEFNKSTD AYELKIANKL FGEKTYLFLQEYLDAIKKFY QTSVESVDFA NAPEESRKKI NSWVESQTNE KIKNLIPEGN IGSNTTLVLV NAIYFKGQWEKKFNKEDTKE EKFWPNKNTY KSIQMMRQYT SFHFASLEDV QAKVLEIPYK GKDLSMIVLL PNEIDGLQKLEEKLTAEKLM EWTSLQNMRE TRVDLHLPRF KVEESYDLKD TLRTMGMVDI FNGDADLSGM TGSRGLVLSGVLHKAFVEVT EEGAEAAAAT AVVGFGSSPT STNEEFHCNH PFLFFIRQNK TNSILFYGRF SSP.
Purity Greaterthan 90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation SERPINB3 protein solution (0.5mg/ml) containing Phosphatebuffered saline (pH7.4),10% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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