Recombinant Human SERPINA1 Protein, Active
Beta LifeScience
SKU/CAT #: BL-4599PS
Recombinant Human SERPINA1 Protein, Active
Beta LifeScience
SKU/CAT #: BL-4599PS
Catalog No.: BL-4599PS
Product Overview
| Tag | N/A |
| Host Species | Human |
| Synonym | Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1, A1AT, PI, A1A, AAT, PI1, MGC9222, PRO2275, MGC23330. |
| Background | SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Defects in SERPINA1 gene can cause emphysema or liver disease. SERPINA1 is an endogenous inhibitor of serine proteases and inhibits the catalytic domain of human recombinant matriptase in vitro. Rise in SERPINA1 occurs as an acute phase response to tissue necrosis and inflammation. mutations in SERPINA1 and SLC11A1 genes change the balance between elastase expressed by leukocytes during phagocytosis. |
| Description | SERPINA1 Human Recombinant expressed in rice is a single, non-glycosylated polypeptide chain containing 384a.a. and having a molecular weight of 43.1 kDa.The SERPINA1 protein is purified by unique purification methods. |
| Source | Rice Grain |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Bioactivity | 3~5 mg SERPINA1 will inhibit 1 mg PPE with an activity of 10.8 units per mg protein |
| Formulation | SERPINA1 was lyophilized from a concentrated solution containing recombinant Albumin. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Lyophilized SERPINA1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SERPINA1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
