Recombinant Human RHOC Protein

Beta LifeScience SKU/CAT #: BL-3502PS
Recombinant Human RHOC Protein

Recombinant Human RHOC Protein

Beta LifeScience SKU/CAT #: BL-3502PS
Catalog No.: BL-3502PS

Product Overview

Tag N/A
Host Species Human
Synonym ARH9, ARHC, H9, RHOH9, RAS-related homolog 9, Rho cDNA clone 9, Rho-related GTP-binding protein RhoC, ARH9, MGC1448, MGC61427, RHOC.
Background RHOC is a small signaling G protein/GTPase which is part of the Rac subfamily of the family Rho family of GTPases. RHOC rotats between inactive GDP-bound and active GTP-bound states and has a role as a molecular switch in signal transduction cascades. RHOC promotes reorganization of the actin cytoskeleton and regulates cell shape, attachment, and motility.
Description RHOC Recombinant Human expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 210a.a. (1-190 a.a.) and having a molecular weight of 23.8 kDa. The RHOC is fused to a 20a.a. His-Tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYIADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRQDEHTRRE LAKMKQEPVR SEEGRDMANR ISAFGYLECS AKTKEGVREV FEMATRAGLQ VRKNKRRRGC.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation RHOC Human 0.5mg/ml solution containing 20mM Tris-HCl pH-8, 0.1M NaCl, 1mM DTT & 20% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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