Recombinant Human RAET1G Protein
Beta LifeScience
SKU/CAT #: BL-4505PS
Recombinant Human RAET1G Protein
Beta LifeScience
SKU/CAT #: BL-4505PS
Catalog No.: BL-4505PS
Product Overview
| Tag | His |
| Host Species | Human |
| Synonym | Retinoic acid early transcript 1G protein, RAET1G, ULBP5. |
| Background | Retinoic Acid Early Transcript 1G (RAET1G/ULBP5) is a member of the MHC class I family. RAET1G functions as a ligand for the NKG2D receptor on the surface of NK cells. NKG2D stimulation influences anti-tumor and anti-viral immune responses of NK cells. ULBP ligands are generated by virally infected cells and tumors. RAET1G is expressed in 2 variants- a membrane and a soluble isoform. RAET1G is highly expressed in the colon and in several tumor cell lines. |
| Description | RAET1G Human Recombinant expressed in E.Coli is a single, non-glycosylated, polypeptide chain (corresponding to Isoform 2, Uniprot accession #Q6H3X3-2) containing 198a.a. including a 10 a.a N-terminal His tag. The total molecular weight is 22.43kDa (calculated). |
| Source | E.coli |
| AA Sequence | MKHHHHHHASGLADPHSLCY DITVIPKFRP GPRWCAVQGQ VDEKTFLHYD CGSKTVTPVS PLGKKLNVTT AWKAQNPVLR EVVDILTEQL LDIQLENYIP KEPLTLQARM SCEQKAEGHG SGSWQLSFDG QIFLLFDSEN RMWTTVHPGA RKMKEKWEND KDMTMSFHYI SMGDCTGWLE DFLMGMDSTL EPSAGGTV. |
| Purity | >95.0% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | RAET1G filtered (0.4 µm) and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl, pH 7.5. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
