Recombinant Human RAET1G Protein

Beta LifeScience SKU/CAT #: BL-4505PS
Recombinant Human RAET1G Protein

Recombinant Human RAET1G Protein

Beta LifeScience SKU/CAT #: BL-4505PS
Catalog No.: BL-4505PS

Product Overview

Tag His
Host Species Human
Synonym Retinoic acid early transcript 1G protein, RAET1G, ULBP5.
Background Retinoic Acid Early Transcript 1G (RAET1G/ULBP5) is a member of the MHC class I family. RAET1G functions as a ligand for the NKG2D receptor on the surface of NK cells. NKG2D stimulation influences anti-tumor and anti-viral immune responses of NK cells. ULBP ligands are generated by virally infected cells and tumors. RAET1G is expressed in 2 variants- a membrane and a soluble isoform. RAET1G is highly expressed in the colon and in several tumor cell lines.
Description RAET1G Human Recombinant expressed in E.Coli is a single, non-glycosylated, polypeptide chain (corresponding to Isoform 2, Uniprot accession #Q6H3X3-2) containing 198a.a. including a 10 a.a N-terminal His tag. The total molecular weight is 22.43kDa (calculated).
Source E.coli
AA Sequence MKHHHHHHASGLADPHSLCY DITVIPKFRP GPRWCAVQGQ VDEKTFLHYD CGSKTVTPVS PLGKKLNVTT AWKAQNPVLR EVVDILTEQL LDIQLENYIP KEPLTLQARM SCEQKAEGHG SGSWQLSFDG QIFLLFDSEN RMWTTVHPGA RKMKEKWEND KDMTMSFHYI SMGDCTGWLE DFLMGMDSTL EPSAGGTV.
Purity >95.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation RAET1G filtered (0.4 µm) and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl, pH 7.5.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
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