Recombinant Human QKI Protein
Beta LifeScience
SKU/CAT #: BL-4129PS
Recombinant Human QKI Protein
Beta LifeScience
SKU/CAT #: BL-4129PS
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Synonym | Hqk, hqkI, QK, QK1, QK3, Protein quaking, QuakingHomolog, KH Domain RNA Binding, RNA Binding Protein HQK, HKQ, KHDomain Containing, RNA Binding. |
Background | KH Domain RNA Binding also known as QKI is aRNA-binding protein which regulates pre-mRNA splicing, export of mRNAs from thenucleus, protein translation, and mRNA stability. QKIis involved in myelinizationand oligodendrocyte differentiation, and it may play a role in schizophrenia.Defects or deletions in the QKIare linked with astrocytic tumors and may be implicated in the pathogenesis ofschizophrenia. Among the diseases associated with QKI are6q terminal deletion syndrome, and schizophrenia. |
Description | QKI Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 364a.a. (1-341 a.a) and having a molecular weight of 40.1kDa.QKI is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods. |
Source | E.coli |
AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSMVGEMET KEKPKPTPDY LMQLMNDKKL MSSLPNFCGI FNHLERLLDE EISRVRKDMY NDTLNGSTEK RSAELPDAVG PIVQLQEKLY VPVKEYPDFN FVGRILGPRG LTAKQLEAET GCKIMVRGKG SMRDKKKEEQ NRGKPNWEHL NEDLHVLITV EDAQNRAEIK LKRAVEEVKK LLVPAAEGED SLKKMQLMEL AILNGTYRDA NIKSPALAFS LAATAQAAPR IITGPAPVLP PAALRTPTPA GPTIMPLIRQ IQTAVMPNGT PHPTAAIVPP GPEAGLIYTP YEYPYTLAPA TSILEYPIEP SGVLGAVATK VRRHDMRVHP YQRIVTADRA ATGN. |
Purity | >85.0% as determined by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Formulation | QKI protein solution (0.25mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |