Recombinant Human POLE3 Protein

Beta LifeScience SKU/CAT #: BL-4409PS
Recombinant Human POLE3 Protein

Recombinant Human POLE3 Protein

Beta LifeScience SKU/CAT #: BL-4409PS
Catalog No.: BL-4409PS

Product Overview

Tag N/A
Host Species Human
Synonym CHARAC17, CHRAC17, p17, YBL1,DNA polymerase epsilon subunit 3, Arsenic-transactivated protein,AsTP, Chromatin accessibility complex 17 kDa protein, HuCHRAC17, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17, POLE3.
Background Polymerase (DNA Directed), Epsilon 3, also know as POLE3, is a histone-fold protein which interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers merge into larger enzymatic complexes for DNA transcription, replication, and packaging.
Description POLE3 Human Recombinant expressed in E. coli is a single polypeptide chain containing 170a.a. (1-147) and having a molecular weight of 19kDa. POLE3 is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMAERPED LNLPNAVITR IIKEALPDGV NISKEARSAI SRAASVFVLY ATSCANNFAM KGKRKTLNAS DVLSAMEEME FQRFVTPLKE ALEAYRREQK GKKEASEQKK KDKDKKTDSE EQDKSRDEDN DEDEERLEEE EQNEEEEVDN.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The POLE3 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Recently viewed