Recombinant Human PNOC Protein

Beta LifeScience SKU/CAT #: BL-4109PS
Recombinant Human PNOC Protein

Recombinant Human PNOC Protein

Beta LifeScience SKU/CAT #: BL-4109PS
Catalog No.: BL-4109PS

Product Overview

Tag N/A
Host Species Human
Synonym Prepronociceptin, Nocistatin, OFQ, Pre-Pro-N/OFQ,Pronociceptin, Orphanin FQ, Nociceptin, PpN/OFQ, N/OFQ, PPNOC.
Background Prepronociceptin (PNOC) is the ligand of the opioid receptor-like receptor (OPRL1). PNOC functions as a transmitter in the brain by modulating nociceptive and locomotor behavior. The PNOC protein may also be involved in neuronal differentiation and development.
Description PNOC Human Recombinant expressed in E.coli is a single, non-glycosylated polypeptide chain containing 180a.a. (20-176) and having a molecular weight of 20.6kDa.PNOC is fused to a 23a.a. His-tag at N-terminus.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSSCQRDCL TCQEKLHPAL DSFDLEVCIL ECEEKVFPSP LWTPCTKVMA RSSWQLSPAA PEHVAAALYQ PRASEMQHLR RMPRVRSLFQ EQEEPEPGME EAGEMEQKQL QKRFGGFTGA RKSARKLANQ KRFSEFMRQY LVLSMQSSQR RRTLHQNGNV.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation PNOC protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.4M urea and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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