Recombinant Human PFN1 Protein

Beta LifeScience SKU/CAT #: BL-4434PS
Recombinant Human PFN1 Protein

Recombinant Human PFN1 Protein

Beta LifeScience SKU/CAT #: BL-4434PS
Catalog No.: BL-4434PS

Product Overview

Tag N/A
Host Species Human
Synonym Profilin-1, Profilin I, PFN1.
Background Profilin1 (PFN1) is a ubiquitous actin monomer-binding protein which is a member of the profilin family. PFN1 significantly boosts skin wound healing in-vitro and in-vivo which may be mediated by purinergic receptors. PFN1 is also active in endothelial cell migration and vessel sprouting. PFN1 is thought to control actin polymerization in response to extracellular signals. PFN1 binds to actin and affects the formation of the cytoskeleton. In addition, PFN1 has an important role in the regulation of epithelial cell-cell adhesion. At high concentrations, profilin averts the polymerization of actin, while at low concentrations it enhances the polymerization. PFN1 gene deletion is linked to Miller-Dieker syndrome.
Description PFN1 Human Recombinant expressed in E.Coli is a single, non-glycosylated, polypeptide chain containing 140a.a. (1-140 a.a.) and having a molecular weight of 15kDa.The PFN1 is purified by unique purification methods.
Source E.coli
AA Sequence MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY.
Purity >95.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The PFN1 protein solution contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Recently viewed