Recombinant Human OSCAR Protein

Beta LifeScience SKU/CAT #: BL-4064PS
Recombinant Human OSCAR Protein

Recombinant Human OSCAR Protein

Beta LifeScience SKU/CAT #: BL-4064PS
Catalog No.: BL-4064PS

Product Overview

Tag N/A
Host Species Human
Synonym PIGR3, Osteoclast-associated immunoglobulin-like receptor, hOSCAR, Polymeric immunoglobulin receptor 3, OSCAR, PIgR-3, PIgR3, Poly-Ig receptor 3.
Background Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. OSCAR plays crucial roles in the regulation of the innate and adaptive immune responses.Unlike the other LRC members, OSCAR expression is found specifically in preosteoclasts or mature osteoclasts. OSCAR is an important bone-specific regulator of osteoclast differentiation. Multiple alternative splicing transcript variants encodes different isoforms have been found for this gene.
Description OSCAR Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 291a.a. (19-286 a.a.) and having a molecular weight of 31kDa.OSCAR is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSDITPSVA IIVPPASYHP KPWLGAQPAT VVTPGVNVTL RCRAPQPAWR FGLFKPGEIA PLLFRDVSSE LAEFFLEEVT PAQGGIYRCC YRRPDWGPGV WSQPSDVLEL LVTEELPRPS LVALPGPVVG PGANVSLRCA GRLRNMSFVL YREGVAAPLQ YRHSAQPWAD FTLLGARAPG TYSCYYHTPS APYVLSQRSE VLVISWEGEG PEARPASSAP GMQAPGPPPS DPGAQAPSLS SFRPRGLVLQ PLLPQTQDSW DPAPPPSDPG V.
Purity >85.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation OSCAR protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M Urea and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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