Recombinant Human OPTC Protein

Beta LifeScience SKU/CAT #: BL-4061PS
Recombinant Human OPTC Protein

Recombinant Human OPTC Protein

Beta LifeScience SKU/CAT #: BL-4061PS
Catalog No.: BL-4061PS

Product Overview

Tag N/A
Host Species Human
Synonym Opticin, Oculoglycan, OPT.
Background Opticin also known as OPTC is a member of the class III of the smallleucine-rich repeat protein (SLRP)family. Members of this family are usually linked with the extracellularmatrix. OPTC is attended in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, opticnerve, choroid, retina, and fetal liver. OPTC might noncovalently bind collagenfibrils and regulate fibril morphology, spacing and organization. OPTC is mappedto a an area of chromosome 1 which is linked with the inherited eye diseasesage-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa(AXPC1).
Description OPTC Human Recombinant expressed in E.Coli is a single, non-glycosylatedpolypeptide chain containing 336a.a. (20-332 a.a) and having amolecular weight of 37.6kDa.OPTC is fused to a 23a.a. His-tag at N-terminusand purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSASLPRKE RKRREEQMPR EGDSFEVLPL RNDVLNPDNY GEVIDLSNYEELTDYGDQLP EVKVTSLAPA TSISPAKSTT APGTPSSNPT MTRPTTAGLL LSSQPNHGLPTCLVCVCLGSSVYCDDIDLE DIPPLPRRTA YLYARFNRIS RIRAEDFKGLTKLKRIDLSN NLISSIDNDA FRLLHALQDL ILPENQLEAL PVLPSGIEFLDVRLNRLQSS GIQPAAFRAM EKLQFLYLSD NLLDSIPGPL PLSLRSVHLQ NNLIETMQRD VFCDPEEHKHTRRQLEDIRL DGNPINLSLF PSAYFCLPRL PIGRFT.
Purity >85% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation OPTC protein solution (0.5mg/ml) containing 20mM Tris-HCl(pH8.0) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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