Recombinant Human OPTC Protein
Beta LifeScience
SKU/CAT #: BL-4061PS
Recombinant Human OPTC Protein
Beta LifeScience
SKU/CAT #: BL-4061PS
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Synonym | Opticin, Oculoglycan, OPT. |
Background | Opticin also known as OPTC is a member of the class III of the smallleucine-rich repeat protein (SLRP)family. Members of this family are usually linked with the extracellularmatrix. OPTC is attended in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, opticnerve, choroid, retina, and fetal liver. OPTC might noncovalently bind collagenfibrils and regulate fibril morphology, spacing and organization. OPTC is mappedto a an area of chromosome 1 which is linked with the inherited eye diseasesage-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa(AXPC1). |
Description | OPTC Human Recombinant expressed in E.Coli is a single, non-glycosylatedpolypeptide chain containing 336a.a. (20-332 a.a) and having amolecular weight of 37.6kDa.OPTC is fused to a 23a.a. His-tag at N-terminusand purified by unique purification methods. |
Source | E.coli |
AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSASLPRKE RKRREEQMPR EGDSFEVLPL RNDVLNPDNY GEVIDLSNYEELTDYGDQLP EVKVTSLAPA TSISPAKSTT APGTPSSNPT MTRPTTAGLL LSSQPNHGLPTCLVCVCLGSSVYCDDIDLE DIPPLPRRTA YLYARFNRIS RIRAEDFKGLTKLKRIDLSN NLISSIDNDA FRLLHALQDL ILPENQLEAL PVLPSGIEFLDVRLNRLQSS GIQPAAFRAM EKLQFLYLSD NLLDSIPGPL PLSLRSVHLQ NNLIETMQRD VFCDPEEHKHTRRQLEDIRL DGNPINLSLF PSAYFCLPRL PIGRFT. |
Purity | >85% as determined by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Formulation | OPTC protein solution (0.5mg/ml) containing 20mM Tris-HCl(pH8.0) and 10% glycerol. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |