Recombinant Human NMI Protein

Beta LifeScience SKU/CAT #: BL-4032PS
Recombinant Human NMI Protein

Recombinant Human NMI Protein

Beta LifeScience SKU/CAT #: BL-4032PS
Catalog No.: BL-4032PS

Product Overview

Tag N/A
Host Species Human
Synonym N-myc (and STAT) Interactor.
Background N-myc-interactor belongs to the oncogene Myc family which has a significant part in cell proliferation, differentiation, and neoplastic transformation. In Addition, NMI cooperates with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA is expressed in small quantities in all human fetal and adult tissues tested except brain and but in large quantities in cancer cell line-myeloid leukemias.
Description NMI expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 327a.a. (1-307a.a.) and having a molecular weight of 37.2kDa.NMI is fused to a 20a.a. His-tag at N-terminus & purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQLK KEIQKLETE LQEATKEFQI KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS MSKHHVQIKDV NLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GVADKILKKKEYPLYINQTC HRVTVSPYTE IHLKKYQIFS GTSKRTVLLT GMEGIQMDEE IVEDLINIHF QRAKNGGGEV DVVKCSLGQP HIAYFEE
Purity >90% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The NMI protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0)1mM DTT and 20% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
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