Recombinant Human NCR3 Protein
Beta LifeScience
SKU/CAT #: BL-4014PS
Recombinant Human NCR3 Protein
Beta LifeScience
SKU/CAT #: BL-4014PS
Catalog No.: BL-4014PS
Product Overview
| Tag | N/A |
| Host Species | Human |
| Synonym | Natural Cytotoxicity Triggering Receptor 3, LY117, 1C7, LymphocyteAntigen 117, Activating Natural Killer Receptor P30, Natural Killer CellP30-Related Protein, NK-p30, NKp30, CD337, MALS, Activating NK-A1 Receptor, CD337Antigen, NKP30. |
| Background | CytotoxicityTriggering Receptor 3 also known as NCR3 is a natural cytotoxicity receptor(NCR) which assists NK cells in the lysis of tumor cells. Moreover, NCR3interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotidepolymorphism in the 5' untranslated region of NCR3 has been related with mildmalaria suceptibility. Three transcript variants encoding various isoforms havebeen found for this gene. |
| Description | NCR3 Human Recombinant expressed in E.Coli is a single,non-glycosylated polypeptide chain containing 141a.a. (19-138 a.a) andhaving a molecular weight of 15.3kDa.NCR3 is fused to a 21a.a. His-tag at N-terminusand purified by unique purification methods. |
| Source | E.coli |
| AA Sequence | MGSSHHHHHH SSGLVPRGSH MLWVSQPPEI RTLEGSSAFL PCSFNASQGR LAIGSVTWFR DEVVPGKEVR NGTPEFRGRLAPLASSRFLH DHQAELHIRD VRGHDASIYV CRVEVLGLGV GTGNGTRLVV EKEHPQLGAG T |
| Purity | Greaterthan 90% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | NCR3 protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
