Recombinant Human NCR3 Protein

Beta LifeScience SKU/CAT #: BL-4014PS
Recombinant Human NCR3 Protein

Recombinant Human NCR3 Protein

Beta LifeScience SKU/CAT #: BL-4014PS
Catalog No.: BL-4014PS

Product Overview

Tag N/A
Host Species Human
Synonym Natural Cytotoxicity Triggering Receptor 3, LY117, 1C7, LymphocyteAntigen 117, Activating Natural Killer Receptor P30, Natural Killer CellP30-Related Protein, NK-p30, NKp30, CD337, MALS, Activating NK-A1 Receptor, CD337Antigen, NKP30.
Background CytotoxicityTriggering Receptor 3 also known as NCR3 is a natural cytotoxicity receptor(NCR) which assists NK cells in the lysis of tumor cells. Moreover, NCR3interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotidepolymorphism in the 5' untranslated region of NCR3 has been related with mildmalaria suceptibility. Three transcript variants encoding various isoforms havebeen found for this gene.
Description NCR3 Human Recombinant expressed in E.Coli is a single,non-glycosylated polypeptide chain containing 141a.a. (19-138 a.a) andhaving a molecular weight of 15.3kDa.NCR3 is fused to a 21a.a. His-tag at N-terminusand purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MLWVSQPPEI RTLEGSSAFL PCSFNASQGR LAIGSVTWFR DEVVPGKEVR NGTPEFRGRLAPLASSRFLH DHQAELHIRD VRGHDASIYV CRVEVLGLGV GTGNGTRLVV EKEHPQLGAG T
Purity Greaterthan 90% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation NCR3 protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
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