Recombinant Human NANOG-TAT Protein
Beta LifeScience
SKU/CAT #: BL-3571PS
Recombinant Human NANOG-TAT Protein
Beta LifeScience
SKU/CAT #: BL-3571PS
Catalog No.: BL-3571PS
Product Overview
| Tag | N/A |
| Host Species | Human |
| Synonym | NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog. |
| Background | NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. |
| Description | NANOG Human Recombinant expressed in E.Coli is a single,non-glycosylated, Polypeptide chain containing304a.a.and c-terminal 13a.a. TAT peptide having a molecular weight of 36.1kDa.The NANOGis purified by unique purification methods. |
| Source | E.coli |
| AA Sequence | VDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR |
| Purity | >95.0% as determined by SDS-PAGE analysis. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | NANOG protein solution contains PBS and 50mM Arginine. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
