Recombinant Human MAF1 Protein

Beta LifeScience SKU/CAT #: BL-3948PS
Recombinant Human MAF1 Protein

Recombinant Human MAF1 Protein

Beta LifeScience SKU/CAT #: BL-3948PS
Catalog No.: BL-3948PS

Product Overview

Tag N/A
Host Species Human
Synonym MAF1 homolog (S. cerevisiae), Repressor of RNA polymerase III transcription MAF1 homolog, homolog of yeast MAF1, MGC20332, MGC31779, MGC39758, DKFZp586G1123.
Background MAF1 resembles Maf1 which is a Saccharomyces cerevisiae - a highly conserved protein in eukaryotic cells, localized to the nucleus. MAF1 Interacts with BRF2, MAF1 and functions as a mediator for signals which explicitly inhibit RNA polymerase III (Pol III) activity by inhibiting the association of TFIIIB to DNA. MAF1 reacts to modifications in the cellular environment and represses pol III transcription.
Description MAF1 Human Recombinant expressed in E.coli is a single, non-glycosylated polypeptide chain containing 276a.a. (1-256) and having a molecular weight of 31.0 kDa.The MAF1 is fused to a 20a.a. His-Tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MKLLENSSFE AINSQLTVET GDAHIIGRIE SYSCKMAGDD KHMFKQFCQE GQPHVLEALS PPQTSGLSPS RLSKSQGGEE EGPLSDKCSR KTLFYLIATL NESFRPDYDF STARSHEFSR EPSLSWVVNA VNCSLFSAVR EDFKDLKPQL WNAVDEEICL AECDIYSYNP DLDSDPFGED GSLWSFNYFF YNKRLKRIVF FSCRSISGST YTPSEAGNEL DMELGEEEVE EESRSRGSGA EETSTMEEDR VPVICI
Purity >90% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The MAF1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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