Recombinant Human KIR2DL5A Protein

Beta LifeScience SKU/CAT #: BL-3395PS
Recombinant Human KIR2DL5A Protein

Recombinant Human KIR2DL5A Protein

Beta LifeScience SKU/CAT #: BL-3395PS
Catalog No.: BL-3395PS

Product Overview

Tag His
Host Species Human
Synonym Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A, Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail 5A, KIR2DL5, CD158F, Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5, Killer Cell Immunoglobulin-Like Receptor KIR2DL5A, Killer Cell Immunoglobulin-Like Receptor 2DL5A, CD158f1 Antigen, KIR2DL5.1, KIR2DL5.3, CD158F1, KIR2DL5A.
Background Killer cell immunoglobulin-like receptor 2DL5A (KIR2DL5A) is a type I transmembrane glycoprotein which is a member of the killer cell Ig-like receptor (KIR) family.KIR2DL5A is detected on the cell surface as a monomer which, upon tyrosine phosphorylation, recruits the Src homology region 2-containing protein tyrosine phosphatase-2. Therefore, KIR2DL5A is an inhibitory receptor gathering a combination of genetic, structural, and functional features unique among KIR, suggesting that KIR2DL5A plays a specialized role in innate immunity.
Description KIR2DL5A Human Recombinant expressed in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 459a.a. (22-238a.a.) and having a molecular weight of 50.5kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). KIR2DL5A is expressed with a 239a.a. hIgG-His tag at C-Terminus and purified by unique purification methods.
Source Sf9
AA Sequence ADPHEGGQDK PLLSAWPSAV VPRGGHVTLL CRSRLGFTIF SLYKEDGVPV PELYNKIFWK SILMGPVTPA HAGTYRCRGS HPRSPIEWSA PSNPLVIVVT GLFGKPSLSA QPGPTVRTGE NVTLSCSSRS SFDMYHLSRE GRAHEPRLPA VPSVNGTFQA DFPLGPATHG GTYTCFGSLH DSPYEWSDPS DPLLVSVTGN SSSSSSSPTE PSSKTGIRRH VEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation KIR2DL5A protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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