Recombinant Human KCNMB3 Protein
Beta LifeScience
SKU/CAT #: BL-3907PS
Recombinant Human KCNMB3 Protein
Beta LifeScience
SKU/CAT #: BL-3907PS
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Synonym | Potassium Channel Subfamily M Regulatory Beta Subunit 3, PotassiumLarge Conductance Calcium-Activated Channel, Subfamily M Beta Member 3, Calcium-ActivatedPotassium Channel, Subfamily M Subunit Beta-3, Charybdotoxin Receptor SubunitBeta-3, Big Potassium Channel Beta Subunit 3, Maxi K Channel Subunit Beta-3, MaxiK Channel Beta-Subunit 3, BK Channel Beta Subunit 3, BKChannel Subunit Beta-3, K(VCA)BETA-3, SLO-BETA-3,BKBETA3, Hbeta3, KCNMB2, KCNMBL, Large Conductance, Voltage And Ca2+ ActivatedPotassium Channel Maxi K Beta 3 Subunit, Calcium-Activated Potassium ChannelRegulatory Subunit, SLOBETA3, Calcium-activated potassium channel subunitbeta-3. |
Background | The KCNMB3 belongs to a family of 4 auxiliary beta subunits found in the mammalian genome, which associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene is comprised of 4 N-terminal alternative exons which produce 4 functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, display kinetically distinct inactivation behaviors. |
Description | KCNMB3 Human Recombinant expressed in E.Coli is a single,non-glycosylated polypeptide chain containing 149a.a. (82-207 a.a) andhaving a molecular weight of 16.8kDa.KCNMB3 is fused to a 23a.a. His-tag at N-terminusand purified by unique purification methods. |
Source | E.coli |
AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQVFVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSEDVILIKKYDQ. |
Purity | Greaterthan 85.0% as determined by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Formulation | KCNMB3protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREAand 10% glycerol. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |