Recombinant Human KCNMB3 Protein

Beta LifeScience SKU/CAT #: BL-3907PS
Recombinant Human KCNMB3 Protein

Recombinant Human KCNMB3 Protein

Beta LifeScience SKU/CAT #: BL-3907PS
Catalog No.: BL-3907PS

Product Overview

Tag N/A
Host Species Human
Synonym Potassium Channel Subfamily M Regulatory Beta Subunit 3, PotassiumLarge Conductance Calcium-Activated Channel, Subfamily M Beta Member 3, Calcium-ActivatedPotassium Channel, Subfamily M Subunit Beta-3, Charybdotoxin Receptor SubunitBeta-3, Big Potassium Channel Beta Subunit 3, Maxi K Channel Subunit Beta-3, MaxiK Channel Beta-Subunit 3, BK Channel Beta Subunit 3, BKChannel Subunit Beta-3, K(VCA)BETA-3, SLO-BETA-3,BKBETA3, Hbeta3, KCNMB2, KCNMBL, Large Conductance, Voltage And Ca2+ ActivatedPotassium Channel Maxi K Beta 3 Subunit, Calcium-Activated Potassium ChannelRegulatory Subunit, SLOBETA3, Calcium-activated potassium channel subunitbeta-3.
Background The KCNMB3 belongs to a family of 4 auxiliary beta subunits found in the mammalian genome, which associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene is comprised of 4 N-terminal alternative exons which produce 4 functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, display kinetically distinct inactivation behaviors.
Description KCNMB3 Human Recombinant expressed in E.Coli is a single,non-glycosylated polypeptide chain containing 149a.a. (82-207 a.a) andhaving a molecular weight of 16.8kDa.KCNMB3 is fused to a 23a.a. His-tag at N-terminusand purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQVFVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSEDVILIKKYDQ.
Purity Greaterthan 85.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation KCNMB3protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREAand 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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