Recombinant Human IPP-POZ Protein

Beta LifeScience SKU/CAT #: BL-3895PS
Recombinant Human IPP-POZ Protein

Recombinant Human IPP-POZ Protein

Beta LifeScience SKU/CAT #: BL-3895PS
Catalog No.: BL-3895PS

Product Overview

Tag N/A
Host Species Human
Synonym Intracisternal A Particle-Promoted Polypeptide,Actin-binding protein IPP, MIPP protein, Kelch-like protein 27, IPP, KLHL27, IPP-POZ.
Background Intracisternal A particle-promoted polypeptide (IPP) is a 66kDa protein (584aa), which contains an N-terminal POZ protein-protein interaction domain and a C-terminal kelch repeat domain consisting of six tandem arranged repeats. The POZ domain (also called BTB domain) is present near the N-terminus of a fraction of zinc finger proteins and in protein that contain the pfam01344 motif such as kelch and pox virus proteins. The BTB/POZ domain mediates homomeric dimerization and in some instances heteromeric dimerization. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-coR and SMRT.
Description IPP-POZ Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 157a.a. & having a molecular weight of 17.3 kDa.
Source E.coli
AA Sequence MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSPYFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLTEVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEF.
Purity >95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The protein (1mg/ml) containing 10mM HEPES (pH7.4) and 25mM NaCl.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
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