Recombinant Human ING1 Protein

Beta LifeScience SKU/CAT #: BL-3370PS
Recombinant Human ING1 Protein

Recombinant Human ING1 Protein

Beta LifeScience SKU/CAT #: BL-3370PS
Catalog No.: BL-3370PS

Product Overview

Tag N/A
Host Species Human
Synonym Inhibitor Of Growth Family, Member 1, Growth Inhibitory Protein ING1, Tumor Suppressor ING1, Growth Inhibitor ING1, Inhibitor Of Growth Protein 1, Inhibitor Of Growth 1, P24ING1c,P33ING1b, P47ING1a, P33ING1, P33, P47, ING1 .
Background Inhibitor of Growth Family Member 1, also known as ING1 is a tumorsuppressor protein which is able to induce cell growth arrest and apoptosis. ING1is a nuclear protein which physically act together with the tumor suppressorprotein TP53 and is a component of the p53 signaling pathway. In addition, Reducedexpression and rearrangement of ING1 have been identified in various cancers.Multiple alternatively spliced transcript variants encoding distinct isoformshave been described for ING1.
Description ING1 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 302a.a. (1-279 a.a) and having a molecular weight of 34.3kDa.ING1 is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMLSPANG EQLHLVNYVE DYLDSIESLP FDLQRNVSLM REIDAKYQEI LKELDECYER FSRETDGAQK RRMLHCVQRA LIRSQELGDE KIQIVSQMVE LVENRTRQVD SHVELFEAQQ ELGDTAGNSG KAGADRPKGE AAAQADKPNS KRSRRQRNNE NRENASSNHD HDDGASGTPK EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD NDECPIEWFH FSCVGLNHKP KGKWYCPKCR GENEKTMDKA LEKSKKERAY NR.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation ING1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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