Recombinant Human HSPA6 Protein

Beta LifeScience SKU/CAT #: BL-3295PS
Recombinant Human HSPA6 Protein

Recombinant Human HSPA6 Protein

Beta LifeScience SKU/CAT #: BL-3295PS
Catalog No.: BL-3295PS

Product Overview

Tag His
Host Species Human
Synonym HSP70B, Heat shock 70 kDa protein 6, Heat shock 70 kDa protein B', HSPA6.
Background HSPA6 is a distinctive member of the human Hsp70 chaperone that takes part in cellular processes such as protein trafficking, folding, and prevention of aggregation. HSPA6 is strictly stress-inducible, having little or no basal expression levels in most cells. HSPA6 and HSP72 are are involved in cell survival of proteotoxic stress.
Description Recombinant Human HSPA6 expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 663a.a. (1-643 a.a) and having a molecular weight of 73.2kDa.HSPA6 human recombinant is fused to a 20a.a. His Tag at N-terminus and purified by conventional chromatography techniques.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MQAPRELAVG IDLGTTYSCV GVFQQGRVEI LANDQGNRTT PSYVAFTDTE RLVGDAAKSQ AALNPHNTVF DAKRLIGRKF ADTTVQSDMK HWPFRVVSEG GKPKVRVCYR GEDKTFYPEE ISSMVLSKMK ETAEAYLGQP VKHAVITVPA YFNDSQRQAT KDAGAIAGLN VLRIINEPTA AAIAYGLDRR GAGERNVLIF DLGGGTFDVS VLSIDAGVFE VKATAGDTHL GGEDFDNRLV NHFMEEFRRK HGKDLSGNKR ALRRLRTACE RAKRTLSSST QATLEIDSLF EGVDFYTSIT RARFEELCSD LFRSTLEPVE KALRDAKLDK AQIHDVVLVG GSTRIPKVQK LLQDFFNGKE LNKSINPDEA VAYGAAVQAA VLMGDKCEKV QDLLLLDVAP LSLGLETAGG VMTTLIQRNA TIPTKQTQTFTTYSDNQPGV FIQVYEGERA MTKDNNLLGR FELSGIPPAP RGVPQIEVTF DIDANGILSV TATDRSTGKA NKITITNDKG RLSKEEVERM VHEAEQYKAE DEAQRDRVAA KNSLEAHVFH VKGSLQEESL RDKIPEEDRR KMQDKCREVL AWLEHNQLAE KEEYEHQKRE LEQICRPIFS RLYGGPGVPG GSSCGTQARQ GDPSTGPIIE EVD.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The HSPA6 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl & 10% Glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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