Recombinant Human Histone H1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2437
Recombinant Human Histone H1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2437
Catalog No.: BLPSN-2437
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | P07305 |
| Synonym | CPN60, GROEL, H10, H1FV, HLD4, HSP60, HSP65, HSPD1, HuCHA60, SPG13 |
| Background | H1 histone family, member (H1F) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-terminal and C-terminal tails. These tails are moderately conserved among species, but differ among variants, suggesting a specific function for each H1 variant. Studies on the role of particular subtypes at specific developmental stages in lower eukaryotes, but also in vertebrates suggest that specific subtypes of H1 participate in particular systems of gene regulation. |
| Description | A DNA sequence encoding the human H1F0 (P07305) (Met 1-Lys 194) was expressed, with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Met 1-Lys 194 |
| Molecular Weight | The recombinant human H1F0 consisting of 205 a.a. and has a calculated molecular mass of 22.4 kDa. It migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions. |
| Purity | >92% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 50mM Tris, 600mM NaCl, 1mM DTT, pH 8.5. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
