Recombinant Human GSTZ1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2354
Recombinant Human GSTZ1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2354
Catalog No.: BLPSN-2354
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_665877.1 |
| Synonym | GSTZ1, GSTZ1-1, MAAI, MAI |
| Background | GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein which has minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. GSTZ1 catalyzes the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. GSTZ1 participates in the catabolism of phenylalanine and tyrosine. Thus defects in GSTZ1 cause harsh metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. |
| Description | A DNA sequence encoding the mature form of human GSTZ1 (NP_665877.1) (Met1-Ala216) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Met1-Ala216 |
| Molecular Weight | The recombinant human GSTZ1 consists of 231 a.a. and predicts a molecular mass of 26 KDa. It migrates as an approximately 27 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, 10% glycerol, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
