Name: Recombinant Human GSTM2 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-2351
Availability: InStock

Recombinant Human GSTM2 Protein (His Tag)

Catalog No.: BLPSN-2351

Product Overview

Tag	His
Host Species	Human
Accession	P28161
Synonym	GST4, GSTM, GSTM2-2, GTHMUS
Background	Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains oneGST C-terminal domain and oneGST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.
Description	A DNA sequence encoding the native human GSTM2 (P28161) (Met 1-Lys 218) was expressed, with a His tag at the N-terminus.
Source	E.coli
Predicted N Terminal	Met
AA Sequence	Met 1-Lys 218
Molecular Weight	The recombinant human GSTM2 consisting of 229 a.a. and has a calculated molecular mass of 27.2 kDa. It migrates as a 27 kDa band in SDS-PAGE under reducing conditions as predicted.
Purity	>97% as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile 50mM Tris, 150mM NaCl, 10mM CaCl2, 0.05% Brig-35, pH 7.5.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.