Recombinant Human GCSH Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2220
Recombinant Human GCSH Protein (His Tag)

Recombinant Human GCSH Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2220
Catalog No.: BLPSN-2220

Product Overview

Tag His
Host Species Human
Accession AAA36011.1
Synonym GCE, NKH
Background Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for GCSH gene. Also, several transcribed and non-transcribed pseudogenes of GCSH gene exist throughout the genome.
Description A DNA sequence encoding the mature form of human GCSH (AAA36011.1) (Ser49-Glu173) was expressed with a His tag at the N-terminus.
Source E.coli
Predicted N Terminal His
AA Sequence Ser49-Glu173
Molecular Weight The recombinant human GCSH consists of 140 a.a. and predicts a molecular mass of 15.7 KDa. It migrates as an approximately 17 KDa band in SDS-PAGE under reducing conditions.
Purity >85% as determined by SDS-PAGE
Endotoxin Please contact us for more information.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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