Recombinant Human GASP-1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2204
Recombinant Human GASP-1 Protein (His Tag)

Recombinant Human GASP-1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2204
Catalog No.: BLPSN-2204

Product Overview

Tag His
Host Species Human
Accession NP_783165.1
Synonym GASP-1, hGASP-1, WFDC20B, WFIKKNRP
Background WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2 and GASP1, is a secreted protein which belongs to theWFIKKN family. WFIKKN2 contains twoBPTI/Kunitz inhibitor domains, oneIg-like C2-type (immunoglobulin-like) domain, oneKazal-like domain, oneNTR domain and oneWAP domain. WFIKKN2 is primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney. WFIKKN2 is protease-inhibitor that contains multiple distinct protease inhibitor domains. It probably has serine protease- and metalloprotease-inhibitor activity. It inhibits the biological activity of mature myostatin, but not activin. WFIKKN2 protein binds mature GDF8/myostatin and myostatin propeptide and inhibits the biological activity of myostatin.
Description A DNA sequence encoding the human WFIKKN2 (NP_783165.1) extracellular domain (Met 1-His 576) was expressed, with a His tag at the C-terminus.
Source HEK293
Predicted N Terminal Leu 35
AA Sequence Met 1-His 576
Molecular Weight The recombinant human WFIKKN2 consists of 553 a.a. and predictes a molecular mass of 61.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhWFIKKN2 is approximately 70-75 kDa due to glycosylation.
Purity >96% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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