Recombinant Human Galectin 7 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2185
Recombinant Human Galectin 7 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2185
Catalog No.: BLPSN-2185
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_002298.1 |
| Synonym | GAL7, LGALS7A |
| Background | LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members in this family. Galectins share similarities in the CRD (the carbohydrate recognition domain). They are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide, galectins can also be stimulated to secretion by non-classical pathways or alternatively targeted to the nucleus. Galectins are implicated in modulating cell-cell and cell-matrix interactions. LGALS7 contains 1 galectin domain and is mainly expressed in stratified squamous epithelium. Galectin-7 could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. LGALS7 is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. |
| Description | A DNA sequence encoding the human LGALS7 (NP_002298.1) (Ser2-Phe136) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Ser2-Phe136 |
| Molecular Weight | The recombinant human LGALS7 consists of 153 a.a. and predicts a molecular mass of 17.2 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Measured by its ability to agglutinate guinea pig red blood cells.The ED50 for this effect is typically 2-10 ug/mL. |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
