Recombinant Human FLRT3 Protein
Beta LifeScience
SKU/CAT #: BL-3819PS
Recombinant Human FLRT3 Protein
Beta LifeScience
SKU/CAT #: BL-3819PS
Catalog No.: BL-3819PS
Product Overview
| Tag | His |
| Host Species | Human |
| Synonym | FibronectinLeucine Rich Transmembrane Protein 3, Fibronectin-Like Domain, Containing Leucine-Rich Transmembrane Protein 3, HH21, Leucine-Rich Repeat, Transmembrane Protein FLRT3,KIAA1469. |
| Background | Fibronectin Leucine Rich Transmembrane Protein3, also known as FLRT3 is a member of the fibronectin leucine richtransmembrane protein (FLRT) family. FLRT3 contains one fibronectin type-IIIdomain as well as 10 LRR (leucine-rich) repeats and is expressed in the kidney,brain, pancreas, skeletal muscle, lung, liver, placenta, and heart. In addition, the members of the FLRT familyplay a role in cell adhesion as well as receptor signaling. FLRT3 has beenimplicated in neurite outgrowth after nerve damage, as a positive regulator ofFGFsignalling and in homotypic cell adhesion. Furthermore, FLRT3 has an essentialfunction in regulating cellular adhesion among the epithelial apical ridge andthe underlying mesenchyme and also in the establishment of the dorso-ventralposition of the ridge. |
| Description | FLRT3 expressed in Sf9 insect cells is a single,glycosylated polypeptide chain containing 508a.a. (29-528a.a.) andhaving a molecular weight of 57.6kDa. (Molecular size on SDS-PAGE will appear atapproximately 70-100kDa).FLRT3 is expressed with an 8a.a. His tag atC-Terminus and purified by unique purification methods. |
| Source | Sf9 |
| AA Sequence | KSCPSVCRCD AGFIYCNDRF LTSIPTGIPE DATTLYLQNN QINNAGIPSDLKNLLKVERI YLYHNSLDEF PTNLPKYVKE LHLQENNIRT ITYDSLSKIP YLEELHLDDN SVSAVSIEEGAFRDSNYLRL LFLSRNHLST IPWGLPRTIE ELRLDDNRIS TISSPSLQGL TSLKRLVLDG NLLNNHGLGDKVFFNLVNLT ELSLVRNSLT AAPVNLPGTN LRKLYLQDNH INRVPPNAFS YLRQLYRLDM SNNNLSNLPQGIFDDLDNIT QLILRNNPWY CGCKMKWVRD WLQSLPVKVN VRGLMCQAPE KVRGMAIKDL NAELFDCKDSGIVSTIQITT AIPNTVYPAQ GQWPAPVTKQPDIKNPKLTK DHQTTGSPSRKTITITVKSV TSDTIHISWK LALPMTALRL SWLKLGHSPA FGSITETIVT GERSEYLVTA LEPDSPYKVC MVPMETSNLYLFDETPVCIE TETAPLRMYN PTTTLNREQE KEPYKNPNLP LEHHHHHH. |
| Purity | Greaterthan 90.0% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | FLRT3protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
