Recombinant Human FIS1 Protein
Beta LifeScience
SKU/CAT #: BL-3818PS
Recombinant Human FIS1 Protein
Beta LifeScience
SKU/CAT #: BL-3818PS
Catalog No.: BL-3818PS
Product Overview
| Tag | His |
| Host Species | Human |
| Synonym | TTC11, Tetratricopeptide repeat domain 11, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae). |
| Background | FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 induces cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. FIS1 participates in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission. |
| Description | FIS1 Human Recombinant expressed in E.Coli is a single, non-glycosylated,polypeptide chain containing 142a.a.(1-122 a.a.) and having a molecular weight of 16.3 kDa. FIS1 protein is fused to a 20a.a. His tag at N-terminus and is purified by standard chromatography. |
| Source | E.coli |
| AA Sequence | MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | FIS1 protein solution (1mg/ml) containing 20mM Tris-HCl pH-8 and 10% glycerol. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
