Recombinant Human FIS1 Protein

Beta LifeScience SKU/CAT #: BL-3818PS
Recombinant Human FIS1 Protein

Recombinant Human FIS1 Protein

Beta LifeScience SKU/CAT #: BL-3818PS
Catalog No.: BL-3818PS

Product Overview

Tag His
Host Species Human
Synonym TTC11, Tetratricopeptide repeat domain 11, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae).
Background FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 induces cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. FIS1 participates in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission.
Description FIS1 Human Recombinant expressed in E.Coli is a single, non-glycosylated,polypeptide chain containing 142a.a.(1-122 a.a.) and having a molecular weight of 16.3 kDa. FIS1 protein is fused to a 20a.a. His tag at N-terminus and is purified by standard chromatography.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG.
Purity >95% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation FIS1 protein solution (1mg/ml) containing 20mM Tris-HCl pH-8 and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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