Recombinant Human FGFR1 Protein (His&GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2054
Recombinant Human FGFR1 Protein (His&GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2054
Catalog No.: BLPSN-2054
Product Overview
| Tag | His&GST |
| Host Species | Human |
| Accession | NP_075594.1 |
| Synonym | FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1, ECCL, fibroblast growth factor receptor 1 |
| Background | Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome.FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, which in addition to FGFR1, includes FGFR2, FGFR3, FGFR4, and FGFRL1. FGFR1-4 are cell surface membrane receptors that possess tyrosine kinase activity. |
| Description | A DNA sequence encoding the human FGFR1 isoform 4 cytoplasmic domain (Gly 311-Arg 731) was fused with the N-terminal His-tagged GST tag at the N-terminus. |
| Source | Insect Cells |
| Predicted N Terminal | Met |
| AA Sequence | Gly 311-Arg 731 |
| Molecular Weight | The recombinant human FGFR1 (aa 311-731) /GST chimera consists of 658 amino acids and has a calculated molecular mass of 75 KDa. It migrates as an approximately 75 KDa band as predicted in SDS-PAGE under reducing conditions. |
| Purity | >93% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Formulation | Recombinant Human FGFR1 Protein (His&GST Tag)Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% glycerol, 0.3mM DTT |
| Stability | Recombinant Human FGFR1 protein is stable up to 1 year at -70°C |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
