Recombinant Human FDCSP Protein

Beta LifeScience SKU/CAT #: BL-3814PS
Recombinant Human FDCSP Protein

Recombinant Human FDCSP Protein

Beta LifeScience SKU/CAT #: BL-3814PS
Catalog No.: BL-3814PS

Product Overview

Tag N/A
Host Species Human
Synonym Follicular dendritic cell secreted peptide, FDC secreted protein, FDC-SP, FDCSP, C4orf7.
Background Follicular Dendritic Cell Secreted Protein (FDCSP) is a small secreted protein which is found in follicular dendritic cells. The FDCSP protein specifically binds to activated B cells, and serves as a regulator of antibody responses. In addition, FDCSP is assumed to contribute to tumor metastases by promoting cancer cell migration and invasion. FDCSP binds to the surface of B-lymphoma cells, but not T-lymphoma cells, which is consistent with a function as a secreted mediator acting upon B-cells. FDCSP is abundantly expressed in the tonsil, lymph node, and tracheam, having a strong expression in the prostate and a lower expression in the thyroid, stomach and colon.
Description FDCSP Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 91a.a. (18-85 a.a) and having a molecular weight of 10.4kDa.FDCSP is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSFPVSQDQ EREKRSISDS DELASGFFVF PYPYPFRPLP PIPFPRFPWF RRNFPIPIPE SAPTTPLPSE K.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation FDCSP protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 7.5), 0.15M NaCl, 50% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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