Recombinant Human EphB4 Protein (His Tag), Biotinylated
Beta LifeScience
SKU/CAT #: BLPSN-1843
Recombinant Human EphB4 Protein (His Tag), Biotinylated
Beta LifeScience
SKU/CAT #: BLPSN-1843
Catalog No.: BLPSN-1843
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_004435.3 |
| Synonym | HTK, MYK1, TYRO11 |
| Background | Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers. |
| Description | A DNA sequence encoding the EPHB4 (NP_004435.3) (Met1-Ala539) was expressed with a C-terminal His tag. The purified protein was biotinylated in vitro. |
| Source | Baculovirus-Insect Cells |
| Predicted N Terminal | Leu 16 |
| AA Sequence | Met1-Ala539 |
| Molecular Weight | The recombinant EPHB4 consists of 535 a.a. and predicts a molecular mass of 58.5 kDa. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile Sterile PBS.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
