Recombinant Human ENO1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1755
Recombinant Human ENO1 Protein (His Tag)

Recombinant Human ENO1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1755
Catalog No.: BLPSN-1755

Product Overview

Tag His
Host Species Human
Accession P06733
Synonym ENO1L1, HEL-S-17, MPB1, NNE, PPH
Background The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make the primary culture follicle granulosa cells in vitro improve progesterone secretion. The over-expression of ENO1 protein can enhance the abilities of proliferation and migration in gastric cancer cells of AGS, which indicates that ENO1 may be an important potential tumor-marker associated with the development of gastric cancer. ENO1 and GPI can be used as markers of human sperm freezability before starting the cryopreservation procedure. The inhibition of ENO1 expression may be a novel strategy for therapy for NHLs patients, and it may be a target for drug resistance.
Description A DNA sequence encoding the human ENO1 (P06733-1) (Met 1-Lys 434) was expressed, with a His tag at the N-terminus.
Source E.coli
Predicted N Terminal Met
AA Sequence Met 1-Lys 434
Molecular Weight The recombinant human ENO1 consisting of 450 a.a. and has a calculated molecular mass of 49.3 kDa. It migrates as an 47 kDa band in SDS-PAGE under reducing conditions as predicted.
Purity >95% as determined by SDS-PAGE
Endotoxin Please contact us for more information.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.5.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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