Recombinant Human DR3 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0098NP
Recombinant Human DR3 Protein (Fc Tag)

Recombinant Human DR3 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0098NP
Catalog No.: BL-0098NP

Product Overview

Tag Fc
Host Species Human
Accession Q93038
Synonym DR3 Tumor necrosis factor receptor superfamily member 25;APO3; DDR3; DR3; TNFRSF12; WSL; WSL1;TNFRSF25;Protein WSL-1;LARD;Protein WSL;Lymphocyte-associated receptor of death;Death receptor 3;Apoptosis-mediating receptor TRAMP;Apoptosis-inducing receptor AIR;Apoptosis-mediating receptor DR3;Apo-3
Background Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) contains 1 death domain and 4 TNFR-Cys repeats. TNFRSF25 is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation, activated by a monogamous ligand, known as TL1A (TNFSF15), which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis. It may play a role in regulating lymphocyte homeostasis.
Description Recombinant Human Death Receptor 3 is expressed by our Mammalian expression system and the target gene encoding Gln25-Phe201 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Gln25-Phe201
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human DR3 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human DR3 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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