Name: Recombinant Human DPP10 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-1646
Availability: InStock

Recombinant Human DPP10 Protein (His Tag)

Catalog No.: BLPSN-1646

Product Overview

Tag	His
Host Species	Human
Accession	Q8N608
Synonym	DPL2, DPPY, DPRP-3, DPRP3
Background	Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein which belongs to thepeptidase S9B family.DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP1 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Genetic variations in DPP1 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
Description	A DNA sequence encoding the human DPP10 isoform 1 (Q8N608-1) extracellular domain (Leu 56-Glu 796) was expressed, with a His tag at the N-terminus.
Source	HEK293
Predicted N Terminal	His
AA Sequence	Leu 56-Glu 796
Molecular Weight	The recombinant human DPP10 consists of 760 a.a. and has a calculated molecular mass of 87.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhDPP10 is approximately 90-110 kDa due to glycosylation.
Purity	>97% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.