Recombinant Human DPEP2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1645
Recombinant Human DPEP2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1645
Catalog No.: BLPSN-1645
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | AAH24021.1 |
| Synonym | MBD2 |
| Background | DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes. |
| Description | A DNA sequence encoding the human DPEP2 (AAH24021.1) (Met1-Ser376) was expressed with a His tag at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Ala 33 |
| AA Sequence | Met1-Ser376 |
| Molecular Weight | The recombinant human DPEP2 consists of 355 a.a. and predicts a molecular mass of 39.4 KDa. It migrates as an approximately 47 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
