Recombinant Human DCXR Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1563
Recombinant Human DCXR Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1563
Catalog No.: BLPSN-1563
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | Q7Z4W1 |
| Synonym | DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR |
| Background | DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and distal sections of the corpus region. HCR2 is weakly or not expressed in brain, lung, heart, spleen and testis. DCXR catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. DCXR participates in the uronate cycle of glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. |
| Description | A DNA sequence encoding the mature form of human DCXR (Q7Z4W1) (Met1-Cys244) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Met1-Cys244 |
| Molecular Weight | The recombinant human DCXR consists of 259 a.a. and predicts a molecular mass of 27.8 KDa. It migrates as an approximately 29 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, 20% Glycerol, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
