Recombinant Human Cyclophilin A / CYPB Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1524
Recombinant Human Cyclophilin A / CYPB Protein (His Tag)

Recombinant Human Cyclophilin A / CYPB Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1524
Catalog No.: BLPSN-1524

Product Overview

Tag His
Host Species Human
Accession NP_000933.1
Synonym CYP-S1, CYPB, HEL-S-39, OI9, SCYLP
Background PPIB is identified as a candidate gene for OI-IX.Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of this disorder have been found, including PPIB, which forms one subunit of the prolyl 3-hydroxylase enzyme complex.Patients with OI caused by PPIB mutation should have appropriate early and regular management of their hearing.
Description A DNA sequence encoding the mature form of human PPIB (NP_000933.1) (Asp 34-Ala 212) was fused with a signal peptide at the N-terminus and a His tag at the C-terminus.
Source HEK293
Predicted N Terminal Asp 34
AA Sequence Asp 34-Ala 212
Molecular Weight The recombinant human PPIB consists of 190 a.a. and migarates as an approximately 22 kDa band in SDS-PAGE under reducing conditions as predicted.
Purity >96% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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