Recombinant Human Cyclophilin A / CYPB Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1524
Recombinant Human Cyclophilin A / CYPB Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1524
Catalog No.: BLPSN-1524
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_000933.1 |
| Synonym | CYP-S1, CYPB, HEL-S-39, OI9, SCYLP |
| Background | PPIB is identified as a candidate gene for OI-IX.Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of this disorder have been found, including PPIB, which forms one subunit of the prolyl 3-hydroxylase enzyme complex.Patients with OI caused by PPIB mutation should have appropriate early and regular management of their hearing. |
| Description | A DNA sequence encoding the mature form of human PPIB (NP_000933.1) (Asp 34-Ala 212) was fused with a signal peptide at the N-terminus and a His tag at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Asp 34 |
| AA Sequence | Asp 34-Ala 212 |
| Molecular Weight | The recombinant human PPIB consists of 190 a.a. and migarates as an approximately 22 kDa band in SDS-PAGE under reducing conditions as predicted. |
| Purity | >96% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
