Recombinant Human CSEN Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1441
Recombinant Human CSEN Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1441
Catalog No.: BLPSN-1441
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | Q9Y2W7 |
| Synonym | CSEN, DREAM, KCHIP3 |
| Background | CSEN, also known as calsenilin and KCNIP3, is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. CSEN also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. CSEN binds to the DRE element of genes including PDYN and FOS. |
| Description | A DNA sequence encoding the human KCNIP3 (Q9Y2W7-1) (Met1-Ile256) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Met1-Ile256 |
| Molecular Weight | The recombinant human KCNIP3 consists of 271 a.a. and predicts a molecular mass of 31.1 KDa. It migrates as an approximately 29 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >85% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 50mM Tris, 100mM NaCl, 10% Glycerol, 1mM DTT, pH 8.0.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
