Recombinant Human CSDC2 Protein

Beta LifeScience SKU/CAT #: BL-3746PS
Recombinant Human CSDC2 Protein

Recombinant Human CSDC2 Protein

Beta LifeScience SKU/CAT #: BL-3746PS
Catalog No.: BL-3746PS

Product Overview

Tag N/A
Host Species Human
Synonym Cold shock domain-containing protein C2, RNA-bindingprotein PIPPin, PIPPIN, DJ347H13.2.
Background Cold shock domain-containing protein C2 (CSDC2) is RNA-binding factor that binds specifically to the very 3'-UTR ends of both histone H1 and H3. 3 mRNAs encompass the polyadenylation signal. The CSDPs (cold shock domain containing proteins) are one group of the evolutionarily conserved nucleic acid-binding proteins extensively distributed in bacteria, plants, animals, and involved in a variety of cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. CSDC2 has a central role in the negative regulation of histone variant synthesis in the developing brain.
Description CSDC2 Human Recombinant expressed in E.coli is a single,non-glycosylated polypeptide chain containing 176a.a. (1-153) andhaving a molecular weight of 19.2kDa. CSDC2 is fused to a 23a.a. His-tagat N-terminus.
Source E.coli
AA Sequence MGSSHHHHHHSSGLVPRGSH MGSMTSESTSPPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFSRSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWSGQVVGS.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The CSDC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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