Name: Recombinant Human COQ7 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-1400
Availability: InStock

Recombinant Human COQ7 Protein (His Tag)

Catalog No.: BLPSN-1400

Product Overview

Tag	His
Host Species	Human
Accession	Q99807
Synonym	CAT5, CLK-1, CLK1
Background	Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical, and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site, a phosphorylation site for protein kinase C and another for casein kinase II, and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.
Description	A DNA sequence encoding the mature form of human COQ7 isoform 1 (Q99807-1) (Ser 37-Leu 217) was fused with a His tag at the C-terminus and a signal peptide at the N-terminus.
Source	HEK293
Predicted N Terminal	Ser 37
AA Sequence	Ser 37-Leu 217
Molecular Weight	The recombinant human COQ7 consists of 192 a.a. and has a predicted molecular mass of 21.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCOQ7 is approximately 20-25 kDa.
Purity	>90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.