Recombinant Human COQ7 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1400
Recombinant Human COQ7 Protein (His Tag)

Recombinant Human COQ7 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1400
Catalog No.: BLPSN-1400

Product Overview

Tag His
Host Species Human
Accession Q99807
Synonym CAT5, CLK-1, CLK1
Background Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical, and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site, a phosphorylation site for protein kinase C and another for casein kinase II, and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.
Description A DNA sequence encoding the mature form of human COQ7 isoform 1 (Q99807-1) (Ser 37-Leu 217) was fused with a His tag at the C-terminus and a signal peptide at the N-terminus.
Source HEK293
Predicted N Terminal Ser 37
AA Sequence Ser 37-Leu 217
Molecular Weight The recombinant human COQ7 consists of 192 a.a. and has a predicted molecular mass of 21.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCOQ7 is approximately 20-25 kDa.
Purity >90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed